Key Factors in Fermentation Broth Selection for Biotech Applications

Fermentation has been used by humans for centuries as a key tool in food preservation and processing, giving rise to products that are essential in the diets of many cultures. However, in recent decades, fermentation processes have transcended their traditional role to become a strategic technology in the industrial and healthcare sectors.

Thanks to the development of increasingly sophisticated culture broths and fermentation media, fermentation is now a fundamental pillar of the healthcare system, enabling the efficient and controlled production of drugs, antibiotics, enzymes, monoclonal antibodies, vaccines, probiotics and other molecules.

From Traditional Fermentation to Controlled Industrial Bioprocesses

The evolution of fermentation into industrial bioprocess has been closely linked to the control of physical, chemical, and biological parameters. Variables such as pH, temperature, aeration, and agitation are essential, but their effectiveness depends largely on the correct formulation of the fermentation broth, which constitutes the metabolic environment where the microorganism or producer cell expresses its maximum biosynthetic potential.

The Fermentation Broth as a Driver of Metabolic Performance

The fermentation broth is not only a source of nutrients, but also a complex system designed to direct cellular metabolism towards the production of the desired metabolite. The selection of carbon, nitrogen, mineral salt, vitamin, and growth factor sources directly influences growth kinetics, productivity, and the quality of the final product, especially in the manufacture of molecules for pharmaceutical use.

Aware of its importance, after years of development, both internally and in collaboration with our customers, we offer a range of broths designed to adapt to different applications and biological systems, including:

Selecting the right fermentation broth is key to maximizing the yield, reproducibility, and quality of any biotechnological process. Our portfolio has been designed to offer reliable solutions tailored to different microorganisms and production strategies, from the laboratory to the industrial plant.

If you have any questions about which medium is best suited to your process, or would like technical advice, please contact us and our team of experts will be happy to help you optimize your fermentations and ensure consistent, high-value results.