A liquid enrichment used for isolating Salmonella typhi and other Salmonella spp. from a variety of sources such as feces, urine, and food. Enzymatic Digest of Casein and Animal Tissue supply nitrogenous substances and carbohydrates for bacterial growth. Sodium Phosphate stabilizes pH and reduces toxicity to Selenite. Sodium Selenite inhibits growth of Gram-positive microorganisms such as coliforms and fecal Streptococci. Lactose is the fermentable carbohydrate and maintains an optimal pH by neutralizing the alkalinization occurring upon Selenite reduction.